Day 1 :
- Diabetes Mellitus
Location: Sydney, Australia
Session Introduction
Martha Rowe
Speech Pathologist
Title: Papaya Enzymes as treatment for Diabetes and Dry Mouth.
Biography:
Martha Rowe, Speech Pathologist since 2000 has spent years researching and developing papaya enzyme formulation as a result of her own difficulties with a dry mouth following surgery due to facial trauma in 2008. She has worked in both Public and Private hospitals across Victoria and has been involved in clinical studies and patients management in the areas of dysphagia and dry mouth.
Abstract:
A Dry mouth syndrome occurs when there is not enough saliva (spit) in the mouth.
A dry mouth is a symptom of an underlying problem, rather than a disease in itself. Causes may include drugs or medication, dehydration, mouth breathing, Sjogren's syndrome, infection, nerve problems and some cancer treatments. People with diabetes often experience issues with a dry mouth. Our research aims were Investigate effects of papaya enzymes in patients who have diabetes with dry mouth, Create a product that super cedes current products on the market, Determine microbiological and immunological outcomes and Investigate Quality of Life Measures. Our results found categorically that papya enzymes assist with maintaining a clean and moistened mouth, free of bacteria and assisted with the increase in saliva flow in patients who have diabetes.
Mohammed Elmujtba Adam Essa
Medical and Cancer Research Institute
Title: Effect of Gum Arabic in Alloxan induced diabetic Millets
Biography:
Mohammmed Elmujtba Adam Essa, 27 years, MBBS, MRCP 1, Co-Founder and CEO of the first nonprofit research institute in Sudan (Cancer and medical Research Institute), dedicated for cancer epidemiology and medical diseases researches and raising awareness, editorial Board Member at Global Journal of Public Health Medicine (GJPHM), chief of research selection committee in Sudanese Medical Associations for Research (SMRA).
Abstract:
Chronic exposure to glucocorticoids (GC) induces obesity, insulin resistance, diabetes which in turn increases diabetes pathophysiology. Heat shock proteins (HSPs) are known to play vital role in reducing diabetic complications by protecting cells and tissues damage. Gum Arabic (GA, Acacia Senegal) a dietary fiber is known to reduce diabetic complications. Here we hypothesized that GA treatment may alter HSPs together with GC generating enzyme gene expression. We investigated the regulation of hepatic HSPs and 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by GA manipulation. 60 rats were divided into 3 groups (n=20 of each): control group, diabetic group injected with Alloxan, and diabetic group which was given 15% GA in drinking water for 9 weeks. The treatment of GA significantly (P<0.05) decreased plasma HSP25 and HSP70 concentrations associated with decreased HSP70, and HSP90 mRNA and protein expression but not HSP25. Interestingly, the treatment of GA decreased a plasma corticosterone concentration which was associated with decreased 11β-hydroxysteroid dehydrogenase type 1 expression mRNA expression in the liver, heart and skeletal muscle of mice compared to the control group. Activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were significantly (P<0.05) increased in GA group compared to diabetic and control groups. GA also significantly (P<0.05) reduced the activities of key liver enzymes, including alanine transaminase (ALT) and aspartate transaminase (AST). The treatment of GA decreased liver malondialdehyde (MDA), while increased glutathione (GSH).Taken together, feeding of GA decreased HSPs and 11β-HSD1 expression both at transcriptional and post-transcriptional levels with improvement oxidant-capacity.
Aghil Absalan
University of Social Welfare and Rehabilitation Sciences Iran
Title: The Effects of Galvanic Vestibular Stimulation on Patients with Type 2 Diabetes
Biography:
Aghil Absalan has his expertise in field of audiology and vestibular science. His PhD thesis was about the role of galvanic vestibular stimulation on management of type 2 diabetic patients. Considering the findings, he try to share and recommend the study findings to internal medicine specialists to be utilized for patients with diabetes.
Abstract:
Type 2 diabetes mellitus is one of the most common diseases of the endocrine secretion glands, characterized by a chronic increase in blood glucose due to impaired secretion and insulin function.
Autonomic nervous system is one of the most important regulators of endocrine glands. Stimulating the parasympathetic part of this system through the vagus nerve leads to stimulation of insulin secretion. Given the synaptic relationship between the vestibular system and the autonomic nervous system and that studies showed that modulating the autonomic nervous system and electrical stimulation of the vagus nerve are effective in reducing the blood sugar in patients with diabetes mellitus, it can be concluded that the stimulation of vestibular nuclei system can be effective in reducing blood sugar levels in such patients.
In the current study, the vestibular system was stimulated by galvanic vestibular stimulation (GVS) in order to evaluate the efficacy of these stimuli in reducing blood glucose in patients with type 2 diabetes mellitus. The control group receiving the false stimulus or sham and the intervention group receiving the GVS.
Comparison of the findings between the two groups showed the effectiveness of GVS in reducing blood glucose in patients with type 2 diabetes mellitus.